In recent years, as Cambodia's road network has improved, so has the bus system. There are now a number of private bus companies running out of Phnom Penh and Siem Reap serving destinations across the country. The hubs are Phnom Penh, Siem Reap and Sihanoukville.
The main operators are Capitol Tours, GST Express, Mailinh, Mekong Express and Phnom Penh Sorya.
Key domestic routes include:
 Phnom Penh - Siem Reap - Phnom Penh
 Phnom Penh - Sihanoukville - Phnom Penh
 Phnom Penh - Kampot - Phnom Penh
 Phnom Penh - Ko Kong - Phnom Penh
 Phnom Penh - Battambang - Phnom Penh
 Phnom Penh - Kratie - Phnom Penh
 Phnom Penh - Kompong Cham - Phnom Penh
 Phnom Penh - Stung Treng - Phnom Penh
 Phnom Penh - Ban Lung - Phnom Penh
 Phnom Penh - Sisophon - Phnom Penh
 Phnom Penh - Poipet - Phnom Penh
 Siem Reap - Battambang - Siem Reap
 Sihanoukville - Kampot - Sihanoukville
Key international routes include:
 Phnom Penh - Ho Chi Minh City - Phnom Penh
 Phnom Penh - Bangkok - Phnom Penh
 Sihanoukville - Ho Chi Minh City - Sihanoukville (via Phnom Penh)
 Siem Reap - Ho Chi Minh City - Siem Reap (via Phnom Penh)